rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2003-2-28
|
pubmed:abstractText |
The metaplastic change of Barrett's oesophagus is linked to both acid and duodenal reflux together with impaired motility. Proton pump inhibitors (PPI) reduce acid reflux, but no treatment is available that reduces duodenogastro-oesophageal reflux (DGOR). The aim of this study was to investigate whether adding a prokinetic to PPI treatment could improve oesophageal motility and subsequently reduce reflux.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0954-691X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
305-12
|
pubmed:dateRevised |
2009-10-16
|
pubmed:meshHeading |
pubmed-meshheading:12610326-Adult,
pubmed-meshheading:12610326-Aged,
pubmed-meshheading:12610326-Anti-Ulcer Agents,
pubmed-meshheading:12610326-Barrett Esophagus,
pubmed-meshheading:12610326-Cisapride,
pubmed-meshheading:12610326-Double-Blind Method,
pubmed-meshheading:12610326-Drug Therapy, Combination,
pubmed-meshheading:12610326-Duodenogastric Reflux,
pubmed-meshheading:12610326-Female,
pubmed-meshheading:12610326-Gastroesophageal Reflux,
pubmed-meshheading:12610326-Gastrointestinal Agents,
pubmed-meshheading:12610326-Humans,
pubmed-meshheading:12610326-Hydrogen-Ion Concentration,
pubmed-meshheading:12610326-Male,
pubmed-meshheading:12610326-Middle Aged,
pubmed-meshheading:12610326-Peristalsis,
pubmed-meshheading:12610326-Proton Pumps
|
pubmed:year |
2003
|
pubmed:articleTitle |
Does the addition of a prokinetic to proton pump inhibitor therapy help reduce duodenogastro-oesophageal reflux in patients with Barrett's oesophagus?
|
pubmed:affiliation |
Academic Surgical Unit, University of Sheffield, UK. a.smythe@sheffield.ac.uk
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|