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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2003-2-25
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pubmed:abstractText |
One of the diagnostic imaging hallmarks of MS is the uptake of IV administered contrast material in new lesions in the brain, signaling blood-brain barrier breakdown and active inflammation. Many clinical drug trials are designed based on the assumption that lesion enhancement on MRI remains visible on average for 1 month. For practical reasons, few serial MRI studies of patients with MS have been performed at intervals shorter than 4 weeks.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1526-632X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
25
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
640-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12601106-Adult,
pubmed-meshheading:12601106-Blood-Brain Barrier,
pubmed-meshheading:12601106-Contrast Media,
pubmed-meshheading:12601106-Disease Progression,
pubmed-meshheading:12601106-Female,
pubmed-meshheading:12601106-Follow-Up Studies,
pubmed-meshheading:12601106-Gadolinium DTPA,
pubmed-meshheading:12601106-Humans,
pubmed-meshheading:12601106-Image Processing, Computer-Assisted,
pubmed-meshheading:12601106-Longitudinal Studies,
pubmed-meshheading:12601106-Magnetic Resonance Imaging,
pubmed-meshheading:12601106-Male,
pubmed-meshheading:12601106-Middle Aged,
pubmed-meshheading:12601106-Multiple Sclerosis, Relapsing-Remitting,
pubmed-meshheading:12601106-Predictive Value of Tests,
pubmed-meshheading:12601106-Recurrence,
pubmed-meshheading:12601106-Sensitivity and Specificity,
pubmed-meshheading:12601106-Time Factors
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pubmed:year |
2003
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pubmed:articleTitle |
MRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals.
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pubmed:affiliation |
Department of Radiology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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