Source:http://linkedlifedata.com/resource/pubmed/id/12574738
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
2003-2-7
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| pubmed:abstractText |
We sought to evaluate whether contrast-enhanced Doppler echocardiography can improve the noninvasive estimation of hemodynamic variables in left ventricular (LV) dysfunction. Right-heart catheterization and Doppler echocardiography were simultaneously performed in 45 patients with LV dysfunction (ejection fraction: 29 +/- 7%) in sinus rhythm. Noninvasive variables were estimated as follows: cardiac output by pulsed Doppler of LV outflow tract; pulmonary capillary wedge pressure by a regression equation including mitral and pulmonary venous flow variables; pulmonary artery mean pressure from the calculated systolic and diastolic pulmonary artery pressures; and pulmonary vascular resistance from the previous measurements according to hemodynamic definition. Contrast enhancement increased the feasibility of pulmonary capillary wedge pressure estimation from 60% to 100%; of pulmonary artery mean pressure from 42% to 91%; and of pulmonary vascular resistance from 42% to 91%. Strong correlations between invasive and noninvasive hemodynamic variables were found: r = 0.90, standard error of the estimate (SEE) 0.45 L/min for cardiac output; r = 0.90, SEE 3.1 mm Hg for pulmonary capillary wedge pressure; r = 0.93, SEE 3.7 mm Hg for pulmonary artery mean pressure; and r = 0.85 SEE 1.0 Wood units for pulmonary vascular resistance. Weaker correlations for PAMP (r = 0.82, SEE 5.6 mm Hg) and PVR (r = 0.66, SEE 1.7 Wood units) were apparent prior to contrast enhancement. When patients were separated according to PVR threshold values, the contrast allowed the correct placement of 88% of patients, whereas only 57% were correctly assigned without it. The contrast increased accuracy and reduced interobserver variability in the evaluation of hemodynamic variables. The contrast-enhanced study is capable of increasing the value of noninvasive hemodynamic assessment in LV dysfunction.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Feb
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| pubmed:issn |
0894-7317
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
16
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
124-31
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| pubmed:dateRevised |
2007-11-15
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| pubmed:meshHeading |
pubmed-meshheading:12574738-Adult,
pubmed-meshheading:12574738-Aged,
pubmed-meshheading:12574738-Cardiomyopathy, Dilated,
pubmed-meshheading:12574738-Chronic Disease,
pubmed-meshheading:12574738-Contrast Media,
pubmed-meshheading:12574738-Echocardiography, Doppler,
pubmed-meshheading:12574738-Female,
pubmed-meshheading:12574738-Hemodynamics,
pubmed-meshheading:12574738-Humans,
pubmed-meshheading:12574738-Image Enhancement,
pubmed-meshheading:12574738-Infusions, Intravenous,
pubmed-meshheading:12574738-Male,
pubmed-meshheading:12574738-Middle Aged,
pubmed-meshheading:12574738-Observer Variation,
pubmed-meshheading:12574738-Polysaccharides,
pubmed-meshheading:12574738-Pulmonary Wedge Pressure,
pubmed-meshheading:12574738-Systole,
pubmed-meshheading:12574738-Vascular Resistance,
pubmed-meshheading:12574738-Ventricular Dysfunction, Left
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| pubmed:year |
2003
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| pubmed:articleTitle |
Contrast-enhanced Doppler hemodynamics for noninvasive assessment of patients with chronic heart failure and left ventricular systolic dysfunction.
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| pubmed:affiliation |
Unità Operativa di Cardiologia, Villamarina Hospital, Pisa, Italy. frank.dini@tiscali.it
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| pubmed:publicationType |
Journal Article,
Evaluation Studies
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