Linked Life Data

12572351

Source:http://linkedlifedata.com/resource/pubmed/id/12572351

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-2-7
pubmed:abstractText
To study acute toxicity of brain tissue caused by 1,2-dichloroethane (1,2-DCE) under static inhalation. The rats were exposed to 1,2-DCE 12 hours by consecutive static inhalation. The morphology changes of brain were observed on different dose of treated rats. Dry weight and wet weight (water content) of brain were investigated too. The results showed that it is no obvious change in morphology and water content when rats were exposed to 1,2-DCE of 2.5 g/m3. The light brain edema appeared when exposed dose was 5.0 g/m3, and the average water content of brain (82.14%) was higher than control group (79.82%), which had significantly difference. The brain morphology of the 10.0 g/m3-group was significant changed compared with that of the control group. The water content of the 10.0 g/m3-group (83.65%) was significantly higher than that of the control group(79.82%) too. The study suggests that 1,2-DCE could result in brain edema when rats inhaled lots of 1,2-DCE in short time.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1000-8020
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
340-1
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
[Study on morphology of brain tissue induced by inhale 1,2-dichloroethane].
pubmed:affiliation
Shanxi Medical University, Taiyuan 030001, China.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't