Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-1-30
pubmed:abstractText
Several lines of evidence indicate that aldosterone antagonists may exert direct antifibrogenic effects. The aim of this study was to evaluate the possible direct antifibrogenic effects of canrenone, the active metabolite of spironolactone, in activated human hepatic stellate cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Aldosterone, http://linkedlifedata.com/resource/pubmed/chemical/Aldosterone Antagonists, http://linkedlifedata.com/resource/pubmed/chemical/Amiloride, http://linkedlifedata.com/resource/pubmed/chemical/Calcium, http://linkedlifedata.com/resource/pubmed/chemical/Canrenone, http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Matrix Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Focal Adhesion Kinase 1, http://linkedlifedata.com/resource/pubmed/chemical/Focal Adhesion Protein-Tyrosine..., http://linkedlifedata.com/resource/pubmed/chemical/Guanidines, http://linkedlifedata.com/resource/pubmed/chemical/PTK2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Platelet-Derived Growth Factor, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Sodium-Hydrogen Antiporter, http://linkedlifedata.com/resource/pubmed/chemical/Sulfones, http://linkedlifedata.com/resource/pubmed/chemical/Thrombin, http://linkedlifedata.com/resource/pubmed/chemical/cariporide, http://linkedlifedata.com/resource/pubmed/chemical/ethylisopropylamiloride
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0016-5085
pubmed:author
pubmed:issnType
Print
pubmed:volume
124
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
504-20
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:12557155-Aldosterone, pubmed-meshheading:12557155-Aldosterone Antagonists, pubmed-meshheading:12557155-Amiloride, pubmed-meshheading:12557155-Calcium, pubmed-meshheading:12557155-Canrenone, pubmed-meshheading:12557155-Cell Division, pubmed-meshheading:12557155-Cell Movement, pubmed-meshheading:12557155-Cells, Cultured, pubmed-meshheading:12557155-Extracellular Matrix Proteins, pubmed-meshheading:12557155-Focal Adhesion Kinase 1, pubmed-meshheading:12557155-Focal Adhesion Protein-Tyrosine Kinases, pubmed-meshheading:12557155-Guanidines, pubmed-meshheading:12557155-Humans, pubmed-meshheading:12557155-Hydrogen-Ion Concentration, pubmed-meshheading:12557155-Intracellular Membranes, pubmed-meshheading:12557155-Liver, pubmed-meshheading:12557155-Liver Cirrhosis, pubmed-meshheading:12557155-Phosphatidylinositol 3-Kinases, pubmed-meshheading:12557155-Phosphorylation, pubmed-meshheading:12557155-Platelet-Derived Growth Factor, pubmed-meshheading:12557155-Protein-Tyrosine Kinases, pubmed-meshheading:12557155-Signal Transduction, pubmed-meshheading:12557155-Sodium-Hydrogen Antiporter, pubmed-meshheading:12557155-Sulfones, pubmed-meshheading:12557155-Thrombin
pubmed:year
2003
pubmed:articleTitle
Antifibrogenic effects of canrenone, an antialdosteronic drug, on human hepatic stellate cells.
pubmed:affiliation
Dipartimento di Medicina Interna, Università di Firenze, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't