Linked Life Data

12541812

Source:http://linkedlifedata.com/resource/pubmed/id/12541812

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-1-24
pubmed:abstractText
A new method for predicting the retention time of solutes under linear gradient elution has been established. In this method, the migration distance of solutes in column and the mobile phase gradient were modified simultaneously according to the distribution of mobile phase in column. The prediction results of retention time of both weakly and strongly retentive solutes were accurate in different instrumental systems using this method. In order to test and verify this method, the retention time of fifteen amino acids and eight homologous compounds of benzene were predicted. The predicted results were compared with those predicted by the method in common use. The relative average errors between predicted and experimental values were 3.70% and 4.90% for the weakly retentive solutes, far smaller than those obtained by the reference method (23.61% and 31.16%). For the strongly retentive solutes, the relative average errors were 0.21% and 6.01% respectively, slightly smaller than those obtained by the reference method (0.81% and 6.69%). It is seen that this new method has many advantages.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1000-8713
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
256-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
[A new method for predicting retention time of solutes under linear gradient elution conditions in RP-HPLC].
pubmed:affiliation
National Chromatographic R. & A. Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116011, China. ycshan@163.net
pubmed:publicationType
Journal Article, English Abstract