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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2003-1-22
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pubmed:abstractText |
Metabolic and regulatory gene networks generally tend to be stable. However, we have recently shown that overexpression of the transcriptional activator Hap4p in yeast causes cells to move to a state characterized by increased respiratory activity. To understand why overexpression of HAP4 is able to override the signals that normally result in glucose repression of mitochondrial function, we analyzed in detail the changes that occur in these cells.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-10449761,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-10592259,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-10641039,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-10684934,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-10742097,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-10788368,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-10835343,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-10884426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-10929718,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-11102521,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-11137008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-11175784,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-11928500,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-12702359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-1812789,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-2005820,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-2061283,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-3005867,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-3065621,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-7286242,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-764877,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-8394810,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-8532532,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-9016498,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-9381177,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-9786867,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12537548-9843981
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1465-6914
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
R3
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:12537548-CCAAT-Binding Factor,
pubmed-meshheading:12537548-Cell Division,
pubmed-meshheading:12537548-Gene Expression Regulation, Fungal,
pubmed-meshheading:12537548-Genes, Fungal,
pubmed-meshheading:12537548-Glucose,
pubmed-meshheading:12537548-Mitochondria,
pubmed-meshheading:12537548-Saccharomyces cerevisiae,
pubmed-meshheading:12537548-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:12537548-Transcription, Genetic,
pubmed-meshheading:12537548-Transcription Factors,
pubmed-meshheading:12537548-Up-Regulation,
pubmed-meshheading:12537548-Zinc
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pubmed:year |
2003
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pubmed:articleTitle |
Hap4p overexpression in glucose-grown Saccharomyces cerevisiae induces cells to enter a novel metabolic state.
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pubmed:affiliation |
Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 SM Amsterdam, The Netherlands. r.lascaris@nki.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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