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rdf:type |
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|
lifeskim:mentions |
|
|
pubmed:issue |
2
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pubmed:dateCreated |
2003-2-24
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|
pubmed:abstractText |
The combination of pindolol with a serotonergic antidepressant has been used to speed up the antidepressant response and to augment in cases of resistant depression. Animal studies have suggested that this increased response occurs because of 5HT(1A) antagonist properties of pindolol, which in combination with a serotonergic antidepressant produces a synergistic increase in 5HT in the synapse.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Mar
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|
pubmed:issn |
0033-3158
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
166
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
102-10
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12536263-Adult,
pubmed-meshheading:12536263-Affect,
pubmed-meshheading:12536263-Anxiety,
pubmed-meshheading:12536263-Blood Pressure,
pubmed-meshheading:12536263-Cross-Over Studies,
pubmed-meshheading:12536263-Drug Therapy, Combination,
pubmed-meshheading:12536263-Eye Movements,
pubmed-meshheading:12536263-Humans,
pubmed-meshheading:12536263-Male,
pubmed-meshheading:12536263-Paroxetine,
pubmed-meshheading:12536263-Pindolol,
pubmed-meshheading:12536263-Pulse,
pubmed-meshheading:12536263-Receptors, Serotonin,
pubmed-meshheading:12536263-Receptors, Serotonin, 5-HT1,
pubmed-meshheading:12536263-Serotonin,
pubmed-meshheading:12536263-Serotonin Uptake Inhibitors,
pubmed-meshheading:12536263-Sleep,
pubmed-meshheading:12536263-Sleep, REM
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pubmed:year |
2003
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|
pubmed:articleTitle |
Effects on sleep architecture of pindolol, paroxetine and their combination in healthy volunteers.
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|
pubmed:affiliation |
Psychopharmacology Unit, School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1TD, UK.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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