Source:http://linkedlifedata.com/resource/pubmed/id/12532665
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
52
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pubmed:dateCreated |
2003-1-20
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pubmed:abstractText |
Based on the improved insight into the mechanism of blood coagulation in vivo, recombinant factor VIIa (rFVIIa) has been developed as a pro-haemostatic agent. It has been shown that this treatment is effective in patients with haemophilia and an inhibiting antibody against a coagulation factor. Administration of rFVIIa can be effective in the treatment of bleeding episodes and the prevention of perioperative blood loss in a number of other coagulation disorders as well. Initial clinical studies indicate that administration of rFVIIa may also reduce blood loss in patients with severe bleeding without pre-existent abnormalities in blood coagulation, but this requires confirmation in additional clinical trials.
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pubmed:commentsCorrections | |
pubmed:language |
dut
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0028-2162
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
146
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2534-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12532665-Autoantibodies,
pubmed-meshheading:12532665-Blood Loss, Surgical,
pubmed-meshheading:12532665-Factor VIIa,
pubmed-meshheading:12532665-Hemophilia A,
pubmed-meshheading:12532665-Hemorrhage,
pubmed-meshheading:12532665-Humans,
pubmed-meshheading:12532665-Recombinant Proteins
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pubmed:year |
2002
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pubmed:articleTitle |
[Treatment and prevention of haemorrhage with recombinant activated factor VII, not only in hemophilia].
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pubmed:affiliation |
Academisch Medisch Centrum/Universiteit van Amsterdam, afd. Inwendige Geneeskunde, Meibergdreef 9, 1105 AZ Amsterdam. m.m.levi@amc.uva.nl
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pubmed:publicationType |
Journal Article,
English Abstract,
Review
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