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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6A
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pubmed:dateCreated |
2003-1-17
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pubmed:abstractText |
Squamous cell carcinomas of the head and neck region (HNSCC) are among the most common malignancies in this area. The VX2 carcinoma of the New Zealand white rabbit metastasizes lymphatically as is the case in HNSCC and therefore, potentially, could be used as a model for HNSCC. Since the family of matrix-metalloproteinases (MMPs) is involved in the process of HNSCC invasion, the aim of this study was to investigate the expression level of MMPs and their specific inhibitors (TIMPs) in the VX2 carcinoma to evaluate if they also play a role in VX2 tumor invasion as observed in human HNSCC.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3281-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12530076-Animals,
pubmed-meshheading:12530076-Carcinoma,
pubmed-meshheading:12530076-Carcinoma, Squamous Cell,
pubmed-meshheading:12530076-Collagenases,
pubmed-meshheading:12530076-Disease Models, Animal,
pubmed-meshheading:12530076-Ear Neoplasms,
pubmed-meshheading:12530076-Head and Neck Neoplasms,
pubmed-meshheading:12530076-Humans,
pubmed-meshheading:12530076-Immunohistochemistry,
pubmed-meshheading:12530076-Matrix Metalloproteinase 13,
pubmed-meshheading:12530076-Matrix Metalloproteinase 3,
pubmed-meshheading:12530076-Rabbits,
pubmed-meshheading:12530076-Tissue Inhibitor of Metalloproteinase-2,
pubmed-meshheading:12530076-Tissue Inhibitor of Metalloproteinase-3
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pubmed:articleTitle |
Expression of MMP-3, MMP-13, TIMP-2 and TIMP-3 in the VX2 carcinoma of the New Zealand white rabbit.
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pubmed:affiliation |
Department of Otorhinolaryngology, Philipps University, Deutschhausstr. 3, 35037 Marburg, Germany.
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pubmed:publicationType |
Journal Article
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