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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2002-12-30
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pubmed:abstractText |
Two alcohol dehydrogenase genes (ADH2 and ADH3 on chromosome 4) and one aldehyde dehydrogenase gene (ALDH2 on chromosome 12) exhibit functional polymorphisms. The goal of this study was to determine whether any associations exist between the ADH2, ADH3, and ALDH2 polymorphisms and alcohol dependence in a group of Native Americans. An additional goal was to determine if any associations exist between these polymorphisms and the endophenotype, maximum number of drinks ever consumed in a 24-hour period.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0002-953X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
160
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
41-6
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:12505800-Adolescent,
pubmed-meshheading:12505800-Adult,
pubmed-meshheading:12505800-Aged,
pubmed-meshheading:12505800-Alcohol Dehydrogenase,
pubmed-meshheading:12505800-Alcohol Drinking,
pubmed-meshheading:12505800-Alcoholism,
pubmed-meshheading:12505800-Aldehyde Dehydrogenase,
pubmed-meshheading:12505800-Alleles,
pubmed-meshheading:12505800-California,
pubmed-meshheading:12505800-Chromosome Mapping,
pubmed-meshheading:12505800-Chromosomes, Human, Pair 12,
pubmed-meshheading:12505800-Chromosomes, Human, Pair 4,
pubmed-meshheading:12505800-Female,
pubmed-meshheading:12505800-Genetic Predisposition to Disease,
pubmed-meshheading:12505800-Genetic Variation,
pubmed-meshheading:12505800-Genotype,
pubmed-meshheading:12505800-Humans,
pubmed-meshheading:12505800-Indians, North American,
pubmed-meshheading:12505800-Male,
pubmed-meshheading:12505800-Middle Aged,
pubmed-meshheading:12505800-Missions and Missionaries,
pubmed-meshheading:12505800-Phenotype,
pubmed-meshheading:12505800-Polymorphism, Genetic,
pubmed-meshheading:12505800-Risk Factors
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pubmed:year |
2003
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pubmed:articleTitle |
Protective association of genetic variation in alcohol dehydrogenase with alcohol dependence in Native American Mission Indians.
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pubmed:affiliation |
Department of Neuropharmacology, Scripps Research Institute, San Diego, CA, USA. twall@ucsd.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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