Linked Life Data

12499585

Source:http://linkedlifedata.com/resource/pubmed/id/12499585

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-12-24
pubmed:abstractText
Null genotype of glutathione S-transferase class me (GSTM1(-)) and the plasma level of malondialdehyde (MDA) were determined in normal subjects, epileptics with good seizure control and epileptics with intractable seizure. The frequency of GSTM1(-) of the epileptics with intractable seizure was significantly higher than that of the group with good seizure control and that of the normal subjects. The average plasma level of MDA of the patients with GSTM1(-) genotype was higher than that of the subjects with GSTM1(+) in either the normal or epileptic group. Thus, the GSTM1(-) genotype may be one of the genetic factors involved in the response to anticonvulsant therapy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0021-5198
pubmed:author
pubmed:issnType
Print
pubmed:volume
90
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
291-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Enhanced lipid peroxidation in epileptics with null genotype of glutathione S-transferase M1 and intractable seizure.
pubmed:affiliation
Department of Neurology & Neuroscience, Changhua Christian Hospital, Taiwan. 26602@cch.org.tw
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't