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pubmed-article:12482434pubmed:abstractTextUsing a known dual PPARalpha/gamma activator (5) as a structural template, SAR evaluations led to the identification of triple PPARalpha/gamma/delta activators (18-20) with equal potency and efficacy on all three receptors. These compounds could become useful tools for studying the combined biological effects of PPARalpha/gamma/delta activation.lld:pubmed
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pubmed-article:12482434pubmed:articleTitleDesign and synthesis of novel PPARalpha/gamma/delta triple activators using a known PPARalpha/gamma dual activator as structural template.lld:pubmed
pubmed-article:12482434pubmed:affiliationNovo Nordisk A/S, Novo Nordisk Park, 2760 Måløv, Denmark. jpm@novonordisk.comlld:pubmed
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