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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0023810,
umls-concept:C0034693,
umls-concept:C0086565,
umls-concept:C0145779,
umls-concept:C0185117,
umls-concept:C0225336,
umls-concept:C0441712,
umls-concept:C0521009,
umls-concept:C0547047,
umls-concept:C1522492,
umls-concept:C2911684
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|
pubmed:issue |
1
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|
pubmed:dateCreated |
2002-12-13
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|
pubmed:abstractText |
To elucidate the mechanism of liver dysfunction occurring in patients with sepsis, we evaluated the effect of bacterial lipopolysaccharide (LPS) on the expression of thrombomodulin (TM) in rat sinusoidal endothelial cells (SECs) and the therapeutic efficacy of exogenous recombinant TM.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0168-8278
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
9-17
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12480554-Animals,
pubmed-meshheading:12480554-Cytokines,
pubmed-meshheading:12480554-Endothelium, Vascular,
pubmed-meshheading:12480554-Escherichia coli,
pubmed-meshheading:12480554-Immunohistochemistry,
pubmed-meshheading:12480554-Lipopolysaccharides,
pubmed-meshheading:12480554-Liver Circulation,
pubmed-meshheading:12480554-Liver Diseases,
pubmed-meshheading:12480554-RNA,
pubmed-meshheading:12480554-RNA, Messenger,
pubmed-meshheading:12480554-Rats,
pubmed-meshheading:12480554-Recombinant Proteins,
pubmed-meshheading:12480554-Thrombomodulin,
pubmed-meshheading:12480554-Thrombosis
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|
pubmed:year |
2003
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pubmed:articleTitle |
Bacterial lipopolysaccharide decreases thrombomodulin expression in the sinusoidal endothelial cells of rats -- a possible mechanism of intrasinusoidal microthrombus formation and liver dysfunction.
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pubmed:affiliation |
Department of Molecular Pathobiology, Mie University School of Medicine, Tsu-city, Mie 514-8507, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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