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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2002-11-26
pubmed:abstractText
Two cases of an unusual morphologic variant of papillary thyroid carcinoma (PTC) are reported. Tumor cells had nuclear features of a typical papillary carcinoma, i.e., overlapping, pale to ground glass and/or grooved nuclei. Tumors were characterized by an extensive stromal component accounting for 40-60% of the tumor. It has been reported that PTC is associated with a variable degree of fibrosis, but the exuberant proliferation of fibroblasts resembling fibromatosis is rare. The histogenesis and clinicopathologic significance of PTC have not been fully clarified because of its rarity. It is possible that the malignant nature of these PTC lesions may be overlooked because attention is focused on the stromal component of the tumor. A diligent search for this variant of papillary carcinoma is important.
pubmed:language
eng
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:author
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
219-25
pubmed:dateRevised
2004-11-17
pubmed:articleTitle
Papillary thyroid carcinoma with fibromatosis-like stroma: a report of two cases.
pubmed:affiliation
Division of Nephrology and Metabolism, Department of Internal Medicine, Tokai University School of Medicine, Bohseidai, Isehara, Japan. 9jmmdoo5@is.icc.u-tokyo.ac.jp