rdf:type |
|
lifeskim:mentions |
umls-concept:C0001554,
umls-concept:C0017262,
umls-concept:C0017797,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C0243043,
umls-concept:C0445204,
umls-concept:C0553534,
umls-concept:C0599946,
umls-concept:C1151471,
umls-concept:C1155266,
umls-concept:C1998811,
umls-concept:C2911684
|
pubmed:issue |
20
|
pubmed:dateCreated |
2002-11-12
|
pubmed:abstractText |
Heat-shock protein 70 (HSP70) plays a major role in the pathophysiology of inflammation, and the induction of HSP70 before the onset of inflammation can reduce organ damage through a self-protective system. Glutamine is known to be an inducer of HSP70, and its preoperative administration seems useful in attenuating cardiopulmonary bypass (CPB)-induced inflammatory response.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/3-nitrotyrosine,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Glutamine,
http://linkedlifedata.com/resource/pubmed/chemical/HSP70 Heat-Shock Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III,
http://linkedlifedata.com/resource/pubmed/chemical/Nitrogen Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Nos2 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Nos3 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Tyrosine
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
1524-4539
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:day |
12
|
pubmed:volume |
106
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2601-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:12427658-Animals,
pubmed-meshheading:12427658-Cardiopulmonary Bypass,
pubmed-meshheading:12427658-Cell Adhesion,
pubmed-meshheading:12427658-Cytokines,
pubmed-meshheading:12427658-Glutamine,
pubmed-meshheading:12427658-HSP70 Heat-Shock Proteins,
pubmed-meshheading:12427658-Heart,
pubmed-meshheading:12427658-Hemodynamics,
pubmed-meshheading:12427658-Inflammation,
pubmed-meshheading:12427658-Male,
pubmed-meshheading:12427658-Myocardium,
pubmed-meshheading:12427658-Neutrophils,
pubmed-meshheading:12427658-Nitric Oxide Synthase,
pubmed-meshheading:12427658-Nitric Oxide Synthase Type II,
pubmed-meshheading:12427658-Nitric Oxide Synthase Type III,
pubmed-meshheading:12427658-Nitrogen Compounds,
pubmed-meshheading:12427658-Preoperative Care,
pubmed-meshheading:12427658-Rats,
pubmed-meshheading:12427658-Rats, Sprague-Dawley,
pubmed-meshheading:12427658-Respiration,
pubmed-meshheading:12427658-Tyrosine
|
pubmed:year |
2002
|
pubmed:articleTitle |
Preoperative glutamine administration induces heat-shock protein 70 expression and attenuates cardiopulmonary bypass-induced inflammatory response by regulating nitric oxide synthase activity.
|
pubmed:affiliation |
Department of Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. hayashi@surg1.med.osaka-u.ac.jp
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pubmed:publicationType |
Journal Article
|