Linked Life Data

1242323

Source:http://linkedlifedata.com/resource/pubmed/id/1242323

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1975-12-18
pubmed:abstractText
1-Adamantanamine (amantadine) pretreatment significantly reduced the motor hyperactivity and hyperthermia caused by d-amphetamine in reserpinized mice. In drug-naive mice, when amantadine was administered after d-amphetamine, the motor activity caused by the latter also was decreased. Since our earlier studies showed that amantadine pretreatment also antagonized the increases in both motor activity and homovanillic acid (HVA) in the caudate nucleus caused by d-amphetamine in mice, it is suggested that the antagonism is due to a competitive blockade at the pre-synaptic level in the brain.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0004-4172
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
780-2
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Blockade of the central effects of d-amphetamine by amantadine. II.
pubmed:publicationType
Journal Article