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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2002-11-7
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pubmed:abstractText |
A synthetic estrogen, diethylstilbestrol (DES), was widely prescribed to pregnant women during the 1950s and 1960s but was later discovered to be associated with an increased risk of clear-cell carcinoma of the vagina and cervix in female offspring. DES has not been linked to other cancers in female offspring, but studies of other prenatal factors such as twin gestation and pre-eclampsia have indicated that in-utero estrogen levels may influence breast cancer risk. We evaluated the relation of in-utero DES exposure to the risk of adult breast cancer.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0957-5243
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pubmed:author |
pubmed-author:ColtonTheodoreT,
pubmed-author:HartgePatriciaP,
pubmed-author:HatchElizabeth EEE,
pubmed-author:HerbstArthur LAL,
pubmed-author:HooverRobert NRN,
pubmed-author:KaufmanRaymond HRH,
pubmed-author:NollerKenneth LKL,
pubmed-author:PalmerJulie RJR,
pubmed-author:RaoR SowmyaRS,
pubmed-author:RosenbergCarol LCL,
pubmed-author:Titus-ErnstoffLindaL,
pubmed-author:TroisiRebeccaR
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pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
753-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12420954-Adult,
pubmed-meshheading:12420954-Breast Neoplasms,
pubmed-meshheading:12420954-Cohort Studies,
pubmed-meshheading:12420954-Diethylstilbestrol,
pubmed-meshheading:12420954-Estrogens, Non-Steroidal,
pubmed-meshheading:12420954-Female,
pubmed-meshheading:12420954-Follow-Up Studies,
pubmed-meshheading:12420954-Humans,
pubmed-meshheading:12420954-Middle Aged,
pubmed-meshheading:12420954-Pregnancy,
pubmed-meshheading:12420954-Prenatal Exposure Delayed Effects,
pubmed-meshheading:12420954-Reproductive History,
pubmed-meshheading:12420954-Risk,
pubmed-meshheading:12420954-Risk Factors
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pubmed:year |
2002
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pubmed:articleTitle |
Risk of breast cancer in women exposed to diethylstilbestrol in utero: prelimiinary results (United States).
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pubmed:affiliation |
Slone Epidemiology Unit, Boston University School of Medicine, MA 02215, USA. jpalmer@slone.bu.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Multicenter Study
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