| pubmed-article:12415310 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12415310 | lifeskim:mentions | umls-concept:C0042789 | lld:lifeskim |
| pubmed-article:12415310 | lifeskim:mentions | umls-concept:C0040300 | lld:lifeskim |
| pubmed-article:12415310 | lifeskim:mentions | umls-concept:C0020962 | lld:lifeskim |
| pubmed-article:12415310 | lifeskim:mentions | umls-concept:C0011923 | lld:lifeskim |
| pubmed-article:12415310 | lifeskim:mentions | umls-concept:C0443224 | lld:lifeskim |
| pubmed-article:12415310 | lifeskim:mentions | umls-concept:C0023693 | lld:lifeskim |
| pubmed-article:12415310 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:12415310 | pubmed:dateCreated | 2002-11-4 | lld:pubmed |
| pubmed-article:12415310 | pubmed:abstractText | Many lymphocyte functions, such as antigen recognition, take place deep in densely populated lymphoid organs. Because direct in vivo observation was not possible, the dynamics of immune-cell interactions have been inferred or extrapolated from in vitro studies. Two-photon fluorescence excitation uses extremely brief (<1 picosecond) and intense pulses of light to 'see' directly into living tissues, to a greater depth and with less phototoxicity than conventional imaging methods. Two-photon microscopy, in combination with newly developed indicator molecules, promises to extend single-cell approaches to the in vivo setting and to reveal in detail the cellular collaborations that underlie the immune response. | lld:pubmed |
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| pubmed-article:12415310 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12415310 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12415310 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12415310 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12415310 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:12415310 | pubmed:issn | 1474-1733 | lld:pubmed |
| pubmed-article:12415310 | pubmed:author | pubmed-author:CahalanMichae... | lld:pubmed |
| pubmed-article:12415310 | pubmed:author | pubmed-author:ParkerIanI | lld:pubmed |
| pubmed-article:12415310 | pubmed:author | pubmed-author:MillerMark... | lld:pubmed |
| pubmed-article:12415310 | pubmed:author | pubmed-author:WeiSindy HSH | lld:pubmed |
| pubmed-article:12415310 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12415310 | pubmed:volume | 2 | lld:pubmed |
| pubmed-article:12415310 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12415310 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12415310 | pubmed:pagination | 872-80 | lld:pubmed |
| pubmed-article:12415310 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
| pubmed-article:12415310 | pubmed:meshHeading | pubmed-meshheading:12415310... | lld:pubmed |
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| pubmed-article:12415310 | pubmed:meshHeading | pubmed-meshheading:12415310... | lld:pubmed |
| pubmed-article:12415310 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12415310 | pubmed:articleTitle | Two-photon tissue imaging: seeing the immune system in a fresh light. | lld:pubmed |
| pubmed-article:12415310 | pubmed:affiliation | Department of Physiology, University of California, Irvine, California 92697-4561, USA. mcalahan@uci.edu | lld:pubmed |
| pubmed-article:12415310 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12415310 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:12415310 | pubmed:publicationType | Review | lld:pubmed |
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