Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1976-6-2
pubmed:abstractText
The effect of one single dose of 10 ng Angiotensin II/kg body weight upon affirmed conditional-reflectory response patterns (two-dimensional conditional-reflectory decision process and periodicities of conditional-reflectory processes) was studied in 50 male albino rats in which a neutrotically induced hypertensive blood pressure regulation had been elicited by stress exposure for 135 days. Contrary to healthy animals in which Angiotensin II was demonstrated to act in a biphasic manner, the neurotic animals revealed a monophasic action manifesting itself by a generalized centralnervous excitation. It was noticed, furthermore, that the information processing and regulatory processes of the CNS are considerably disturbed. The chronically hypertensive systolic blood pressure values of neurotic animals, like in healthy ones, show a brief, transient rise immediately following administration of Angiotensin II. These results are not only another proof of a neurotropic component of Angiotensin II action, but they show also that this action allows one to judge the state of disturbed nervous functions. The correlation of the neurotropic effect of Angiotensin II with pathogenetic mechanisms of experimental neurotically induced hypertension is discussed.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5318
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1453-64
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
[Effect of angiotensin II on the conditional relfex response patterns of neurotic albino rats].
pubmed:publicationType
Journal Article, English Abstract