Source:http://linkedlifedata.com/resource/pubmed/id/12401500
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2002-10-28
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pubmed:abstractText |
To assess human exposure to bisphenol A (BPA) over a 10-year period, BPA concentrations in maternal serum (MS) and amniotic fluid (AF) obtained at early second trimester were determined. ELISA was used to measure BPA in 200 MS/AF pairs in women carrying fetuses with normal karyotypes (Group I) and in 48 pairs with abnormal karyotypes (Group II). In Group I, BPA concentrations in AF (median: 0.26 ng/ml) were lower (P<0.01) than in MS (2.24 ng/ml). Over a 10-year period, yearly BPA concentrations in MS decreased from 5.62 to 0.99 ng/ml (P<0.001). Eight of the Group I AF samples had relatively high concentrations of BPA (2.80-5.62 ng/ml). In Group II, BPA concentrations in AF (0 ng/ml) were lower (P<0.01) than in MS (2.97 ng/ml). MS BPA concentrations in Group II were higher (P<0.01) than in Group I.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0890-6238
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
735-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12401500-Adult,
pubmed-meshheading:12401500-Amniotic Fluid,
pubmed-meshheading:12401500-Environmental Exposure,
pubmed-meshheading:12401500-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:12401500-Estrogens, Non-Steroidal,
pubmed-meshheading:12401500-Female,
pubmed-meshheading:12401500-Humans,
pubmed-meshheading:12401500-Japan,
pubmed-meshheading:12401500-Karyotyping,
pubmed-meshheading:12401500-Phenols,
pubmed-meshheading:12401500-Pregnancy,
pubmed-meshheading:12401500-Pregnancy Trimester, Second
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pubmed:articleTitle |
Maternal serum and amniotic fluid bisphenol A concentrations in the early second trimester.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Kita-ku N15 W7, Sapporo 060-8638, Japan. yhideto@med.hokudai.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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