|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2002-10-25
|
|
pubmed:abstractText |
Organ transplant recipients currently require lifetime immunosuppressive therapy, with its accompanying side effects. Biological agents that block T-cell costimulatory pathways are important components of strategies being developed to induce transplantation tolerance. The aim of this study was to test the effect of a novel chimeric anti-human CD40 monoclonal antibody (Chi 220), either alone or in combination with CTLA4-Ig, on the survival of renal allografts in a nonhuman primate model.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD28,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD40,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation,
http://linkedlifedata.com/resource/pubmed/chemical/CD40 Ligand,
http://linkedlifedata.com/resource/pubmed/chemical/CTLA-4 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/CTLA4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoconjugates,
http://linkedlifedata.com/resource/pubmed/chemical/Immunosuppressive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Isoantibodies,
http://linkedlifedata.com/resource/pubmed/chemical/abatacept
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0041-1337
|
|
pubmed:author |
pubmed-author:AndersonDaniel CDC,
pubmed-author:AruffoAlejandroA,
pubmed-author:BrayRobertR,
pubmed-author:CowanShannonS,
pubmed-author:HennigarRandallR,
pubmed-author:HollenbaughDianeD,
pubmed-author:LarsenChristian PCP,
pubmed-author:LinAngelloA,
pubmed-author:OdomKrisK,
pubmed-author:PearsonThomas CTC,
pubmed-author:SiadakAnthony WAW,
pubmed-author:StrobertElizabethE,
pubmed-author:TrambleyJoelJ
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
74
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
933-40
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:12394833-Animals,
pubmed-meshheading:12394833-Antibodies,
pubmed-meshheading:12394833-Antibodies, Monoclonal,
pubmed-meshheading:12394833-Antibody Formation,
pubmed-meshheading:12394833-Antigens, CD,
pubmed-meshheading:12394833-Antigens, CD28,
pubmed-meshheading:12394833-Antigens, CD40,
pubmed-meshheading:12394833-Antigens, Differentiation,
pubmed-meshheading:12394833-B-Lymphocytes,
pubmed-meshheading:12394833-CD40 Ligand,
pubmed-meshheading:12394833-CTLA-4 Antigen,
pubmed-meshheading:12394833-Cytomegalovirus Infections,
pubmed-meshheading:12394833-Drug Therapy, Combination,
pubmed-meshheading:12394833-Graft Survival,
pubmed-meshheading:12394833-Immunoconjugates,
pubmed-meshheading:12394833-Immunosuppressive Agents,
pubmed-meshheading:12394833-Isoantibodies,
pubmed-meshheading:12394833-Kidney,
pubmed-meshheading:12394833-Kidney Transplantation,
pubmed-meshheading:12394833-Macaca mulatta,
pubmed-meshheading:12394833-Male,
pubmed-meshheading:12394833-Tissue Donors,
pubmed-meshheading:12394833-Transplantation, Homologous
|
|
pubmed:year |
2002
|
|
pubmed:articleTitle |
Anti-CD40 therapy extends renal allograft survival in rhesus macaques.
|
|
pubmed:affiliation |
Emory Transplant Center, Department of Surgery, Emory University, Atlanta, Georgia 30322, USA.
|
|
pubmed:publicationType |
Journal Article
|
