rdf:type |
|
lifeskim:mentions |
umls-concept:C0005768,
umls-concept:C0011696,
umls-concept:C0017337,
umls-concept:C0026809,
umls-concept:C0232338,
umls-concept:C0392673,
umls-concept:C0392747,
umls-concept:C0442802,
umls-concept:C0443172,
umls-concept:C0679058,
umls-concept:C1547699,
umls-concept:C2700640
|
pubmed:issue |
10
|
pubmed:dateCreated |
2002-10-14
|
pubmed:abstractText |
Desmin, an intermediate filament, has a key role in the integrity of myocytes, and its absence induces cardiomyopathies. Mice lacking desmin (Des-/- group) exhibit microvascular dysfunction leading to smooth muscle hyporeactivity. We investigated the effect of the absence of desmin in mice (Des-/- mice versus Des+/+ mice) on the adaptation of mesenteric arteries to changes in blood flow.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1524-4636
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:day |
1
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1579-84
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12377733-Adaptation, Physiological,
pubmed-meshheading:12377733-Animals,
pubmed-meshheading:12377733-Desmin,
pubmed-meshheading:12377733-Endothelium, Vascular,
pubmed-meshheading:12377733-Ligation,
pubmed-meshheading:12377733-Male,
pubmed-meshheading:12377733-Mesenteric Arteries,
pubmed-meshheading:12377733-Mice,
pubmed-meshheading:12377733-Mice, Mutant Strains,
pubmed-meshheading:12377733-Microcirculation,
pubmed-meshheading:12377733-Muscle, Smooth, Vascular,
pubmed-meshheading:12377733-Muscular Diseases,
pubmed-meshheading:12377733-Regional Blood Flow
|
pubmed:year |
2002
|
pubmed:articleTitle |
Excessive microvascular adaptation to changes in blood flow in mice lacking gene encoding for desmin.
|
pubmed:affiliation |
Institut National de la Santé et de la Recherche Médicale U 541, IFR Circulation-Paris-Nord, Paris, France.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|