|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
14
|
|
pubmed:dateCreated |
2002-10-1
|
|
pubmed:abstractText |
Tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA) are thought to play critical roles in vascular remodeling after injury, with tPA mediating intravascular clot lysis and uPA modulating cell migration within the vessel wall. In human vascular disease, however, thrombus organization and neointimal formation are closely interrelated processes. This study examines the differential roles of tPA and uPA in these processes in mice.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
1524-4539
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
1
|
|
pubmed:volume |
106
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1847-52
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:12356640-Animals,
pubmed-meshheading:12356640-Carotid Arteries,
pubmed-meshheading:12356640-Carotid Stenosis,
pubmed-meshheading:12356640-Cell Count,
pubmed-meshheading:12356640-Chlorides,
pubmed-meshheading:12356640-Disease Models, Animal,
pubmed-meshheading:12356640-Ferric Compounds,
pubmed-meshheading:12356640-Hemodynamics,
pubmed-meshheading:12356640-Macrophages,
pubmed-meshheading:12356640-Mice,
pubmed-meshheading:12356640-Mice, Inbred C57BL,
pubmed-meshheading:12356640-Mice, Knockout,
pubmed-meshheading:12356640-RNA, Messenger,
pubmed-meshheading:12356640-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12356640-Tissue Plasminogen Activator,
pubmed-meshheading:12356640-Tunica Intima,
pubmed-meshheading:12356640-Tunica Media,
pubmed-meshheading:12356640-Urokinase-Type Plasminogen Activator,
pubmed-meshheading:12356640-Vascular Patency,
pubmed-meshheading:12356640-Wound Healing
|
|
pubmed:year |
2002
|
|
pubmed:articleTitle |
Different mechanisms of increased luminal stenosis after arterial injury in mice deficient for urokinase- or tissue-type plasminogen activator.
|
|
pubmed:affiliation |
Georg August University, Department of Cardiology and Pulmonary Medicine, Goettingen, Germany.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
