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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2002-9-27
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pubmed:abstractText |
The acyclic peptide tasiamide (1) has been isolated from the marine cyanobacterium Symploca sp. The planar structure and absolute stereochemistry of the peptide were deduced by 2D NMR techniques and chiral HPLC. Tasiamide (1) was cytotoxic against KB and LoVo cells with IC(50) values of 0.48 and 3.47 microg/mL, respectively.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0163-3864
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1336-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12350160-Cell Survival,
pubmed-meshheading:12350160-Chromatography, High Pressure Liquid,
pubmed-meshheading:12350160-Cyanobacteria,
pubmed-meshheading:12350160-Drug Screening Assays, Antitumor,
pubmed-meshheading:12350160-Humans,
pubmed-meshheading:12350160-KB Cells,
pubmed-meshheading:12350160-Molecular Structure,
pubmed-meshheading:12350160-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:12350160-Oligopeptides,
pubmed-meshheading:12350160-Palau,
pubmed-meshheading:12350160-Spectroscopy, Fourier Transform Infrared,
pubmed-meshheading:12350160-Stereoisomerism
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pubmed:year |
2002
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pubmed:articleTitle |
Tasiamide, a cytotoxic peptide from the marine cyanobacterium Symploca sp.
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pubmed:affiliation |
Department of Chemistry, University of Hawaii at Manoa, Honolulu 96822, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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