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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1975-5-17
|
| pubmed:abstractText |
An attempt was made to derive a useful noninvasive index to evalute a change in myocardial contractile state using transcutaneous Doppler flow-velocity curve from the carotid artery. In 5 mongrel dogs and in 43 patients with various heart disease, Doppler flow velocity curves were obtained from the ascending aorta intravascularly using a Doppler catheter and/or from carotid artery transcutaneously using a Doppler probe. The first derivative of left ventricular pressure (dp/dt) and electrocardiogram (ECG) were recorded simultaneously. The following 3 indices were measured from the Doppler flow-velocity curves: (1) macimum acceleration of blood flow (dv/dt), (2) time from onset of ejection to peak flow (time-to-peak), (3) time interval between the beginning of Q wave of ECG to the peak of Doppler flow velocity curve (ECG Q-Doppler peak). Among these 3 indices, only ECG Q-Doppler peak demonstrated a significant correlation between the values measured intravascularly and transcutaneously. Also, only ECG Q-Doppler peak showed significant correlation with maximum of dp/dt (max dp/dt). Since ECG Q-Doppler peak showed correlation with heart rate, the difference between observed and predicted ECG Q-Doppler peak (delta ECG Q-Doppler peak) was calculated to exclude the effect of heart rate. Predicted value of ECG Q-Doppler peak was calculated from the regression equation between heart rate and ECG Q-Doppler peak in the separate experiments. There was significant correlation between delta ECG Q-Doppler peak and max dp/dt. In 15 patients with coronary artery disease and in 16 healthy subjects, delta ECG Q-Doppler peak and the other noninvasive method (systolic time intervals) were measured. Delta ECG Q-Doppler peak showed better result in the separation of 2 groups than by systolic timeintervals. It was concluded that delta ECG Q-Doppler peak is a useful index to evaluate the myocardial contractile state since this index is readily obtained noninvasively.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0021-4868
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
16
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
22-35
|
| pubmed:dateRevised |
2009-11-3
|
| pubmed:meshHeading |
pubmed-meshheading:123016-Adolescent,
pubmed-meshheading:123016-Adult,
pubmed-meshheading:123016-Aged,
pubmed-meshheading:123016-Angina Pectoris,
pubmed-meshheading:123016-Animals,
pubmed-meshheading:123016-Blood Flow Velocity,
pubmed-meshheading:123016-Carotid Arteries,
pubmed-meshheading:123016-Child,
pubmed-meshheading:123016-Child, Preschool,
pubmed-meshheading:123016-Dogs,
pubmed-meshheading:123016-Electrocardiography,
pubmed-meshheading:123016-Female,
pubmed-meshheading:123016-Heart,
pubmed-meshheading:123016-Heart Catheterization,
pubmed-meshheading:123016-Heart Rate,
pubmed-meshheading:123016-Humans,
pubmed-meshheading:123016-Male,
pubmed-meshheading:123016-Middle Aged,
pubmed-meshheading:123016-Myocardial Infarction,
pubmed-meshheading:123016-Pressure,
pubmed-meshheading:123016-Rheology,
pubmed-meshheading:123016-Ventricular Function
|
| pubmed:year |
1975
|
| pubmed:articleTitle |
Blood flow velocity in the carotid artery as a measure of myocardial contractility.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|