Source:http://linkedlifedata.com/resource/pubmed/id/12242548
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2002-9-20
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pubmed:abstractText |
Recent studies have revealed autonomic dysfunction in amyotrophic lateral sclerosis (ALS). We studied salivary gland function by quantitative scintigraphy in ALS patients (n = 30) and healthy controls (n = 30). Uptake of (99m)Tc-pertechnetate in the parotid and submandibular glands was significantly decreased in ALS patients. No correlation was found between radiotracer uptake and regions of onset (bulbar-limb), duration of disease, or functional scores. Our data show early subclinical autonomic involvement supporting the view that ALS is a multisystem degenerative disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0340-5354
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
249
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1246-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12242548-Aged,
pubmed-meshheading:12242548-Amyotrophic Lateral Sclerosis,
pubmed-meshheading:12242548-Autonomic Nervous System Diseases,
pubmed-meshheading:12242548-Cohort Studies,
pubmed-meshheading:12242548-Female,
pubmed-meshheading:12242548-Humans,
pubmed-meshheading:12242548-Male,
pubmed-meshheading:12242548-Middle Aged,
pubmed-meshheading:12242548-Radionuclide Imaging,
pubmed-meshheading:12242548-Salivary Glands,
pubmed-meshheading:12242548-Statistics, Nonparametric
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pubmed:year |
2002
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pubmed:articleTitle |
Impaired salivary gland function reveals autonomic dysfunction in amyotrophic lateral sclerosis.
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pubmed:affiliation |
Department of Neurology, University of Wuerzburg, Germany. ralf.giess@mail.uni-wuerzburg.de
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pubmed:publicationType |
Journal Article,
Comparative Study
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