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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2002-9-16
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pubmed:abstractText |
Transfer of growth-suppressive genes to lung tumors has therapeutic potential, but effective delivery techniques have not been developed. Here, we investigated gene delivery to lung tumors by aerosolization of adenoviral vectors incorporated into calcium phosphate precipitates.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2970-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12231543-Adenocarcinoma,
pubmed-meshheading:12231543-Adenoviridae,
pubmed-meshheading:12231543-Aerosols,
pubmed-meshheading:12231543-Alleles,
pubmed-meshheading:12231543-Amino Acid Substitution,
pubmed-meshheading:12231543-Animals,
pubmed-meshheading:12231543-Exons,
pubmed-meshheading:12231543-Gene Therapy,
pubmed-meshheading:12231543-Genes, Dominant,
pubmed-meshheading:12231543-Genes, Reporter,
pubmed-meshheading:12231543-Genes, ras,
pubmed-meshheading:12231543-Genetic Vectors,
pubmed-meshheading:12231543-Humans,
pubmed-meshheading:12231543-Lac Operon,
pubmed-meshheading:12231543-Lung Neoplasms,
pubmed-meshheading:12231543-MAP Kinase Kinase 4,
pubmed-meshheading:12231543-Mice,
pubmed-meshheading:12231543-Mitogen-Activated Protein Kinase Kinases,
pubmed-meshheading:12231543-Point Mutation,
pubmed-meshheading:12231543-Signal Transduction,
pubmed-meshheading:12231543-Xenograft Model Antitumor Assays
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pubmed:year |
2002
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pubmed:articleTitle |
Inhibition of oncogenic K-ras signaling by aerosolized gene delivery in a mouse model of human lung cancer.
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pubmed:affiliation |
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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