Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2002-9-16
pubmed:abstractText
Several studies have described polymorphisms in the genes encoding interleukin-1alpha (IL-1alpha) and IL-1beta cytokines and their implication in the onset of Alzheimer disease or in linkage disequilibrium with an as yet to be identified second locus on chromosome 2. However, these results have been associated with the sporadic forms of Alzheimer disease. Here we present data on the effects of the interleukin 1-beta exonic polymorphism (+3953) using a series of cohort healthy control samples and in vitro protein secretion assays.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0014-4800
pubmed:author
pubmed:issnType
Print
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
139-41
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
The Interleukin 1-beta exonic (+3953) polymorphism does not alter in vitro protein secretion.
pubmed:affiliation
Institute of Biomedical Sciences, Department of Neurology, Ospedale Luigi Sacco, Milan, Italy
pubmed:publicationType
Journal Article, Comparative Study, In Vitro