| pubmed-article:1221925 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1221925 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:1221925 | lifeskim:mentions | umls-concept:C0024143 | lld:lifeskim |
| pubmed-article:1221925 | lifeskim:mentions | umls-concept:C0237881 | lld:lifeskim |
| pubmed-article:1221925 | lifeskim:mentions | umls-concept:C0220901 | lld:lifeskim |
| pubmed-article:1221925 | lifeskim:mentions | umls-concept:C0750502 | lld:lifeskim |
| pubmed-article:1221925 | lifeskim:mentions | umls-concept:C0449774 | lld:lifeskim |
| pubmed-article:1221925 | lifeskim:mentions | umls-concept:C1516240 | lld:lifeskim |
| pubmed-article:1221925 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:1221925 | pubmed:dateCreated | 1976-6-2 | lld:pubmed |
| pubmed-article:1221925 | pubmed:abstractText | The time course of DNA binding capacity (DNA-bc) was found to correlate with the clinical course in a group of 21 patients who had biopsy-proven lupus glomerulonephritis and were treated with immunosuppressive agents. Eight patients showed a sequential DNA-bc pattern in which a high titre of anti-DNA antibody was present for a prolonged period of time all having an unfavourable clinical course. Persistently high values of DNA-bc preceded by as much as 10 months evidence of renal deterioration obtained by conventional renal function tests. Thirteen patients showed a low titre of anti-DNA antibody throughout most of their course, 12 having a favourable outcome. An initially high value of DNA-bc had no prognostic significance. These results suggest that the persistence of a high titre of anti-DNA antibody in patients with lupus glomerulonephritis is a poor prognostic sign. | lld:pubmed |
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| pubmed-article:1221925 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1221925 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1221925 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1221925 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1221925 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:1221925 | pubmed:issn | 0003-4967 | lld:pubmed |
| pubmed-article:1221925 | pubmed:author | pubmed-author:BaumgartenAA | lld:pubmed |
| pubmed-article:1221925 | pubmed:author | pubmed-author:SiegelN JNJ | lld:pubmed |
| pubmed-article:1221925 | pubmed:author | pubmed-author:HechtBB | lld:pubmed |
| pubmed-article:1221925 | pubmed:author | pubmed-author:AdlerM KMK | lld:pubmed |
| pubmed-article:1221925 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1221925 | pubmed:volume | 34 | lld:pubmed |
| pubmed-article:1221925 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1221925 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1221925 | pubmed:pagination | 444-50 | lld:pubmed |
| pubmed-article:1221925 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:1221925 | pubmed:meshHeading | pubmed-meshheading:1221925-... | lld:pubmed |
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| pubmed-article:1221925 | pubmed:meshHeading | pubmed-meshheading:1221925-... | lld:pubmed |
| pubmed-article:1221925 | pubmed:year | 1975 | lld:pubmed |
| pubmed-article:1221925 | pubmed:articleTitle | Prognostic significance of DNA-binding capacity patterns in patients with lupus nephritis. | lld:pubmed |
| pubmed-article:1221925 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1221925 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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