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rdf:type |
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lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0013117,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0023418,
umls-concept:C0031727,
umls-concept:C0037083,
umls-concept:C0086418,
umls-concept:C0205263,
umls-concept:C0332206,
umls-concept:C0538571,
umls-concept:C1516044,
umls-concept:C1539477,
umls-concept:C1710082,
umls-concept:C1825644
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pubmed:issue |
9
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pubmed:dateCreated |
2002-9-9
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pubmed:abstractText |
The apoptotic Bcl-2 family member Hrk is transcriptionally silenced via DREAM in hematopoietic progenitor cell lines, and is specifically induced after growth factor withdrawal. Given that expression of Hrk is sufficient to induce apoptosis, we studied the expression of this apoptotic protein and its regulatory mechanism in human leukemia cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD95,
http://linkedlifedata.com/resource/pubmed/chemical/Bcr-Abl tyrosine kinase,
http://linkedlifedata.com/resource/pubmed/chemical/CASP3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Caspases,
http://linkedlifedata.com/resource/pubmed/chemical/DNA,
http://linkedlifedata.com/resource/pubmed/chemical/Fusion Proteins, bcr-abl,
http://linkedlifedata.com/resource/pubmed/chemical/KCNIP3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Kv Channel-Interacting Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Repressor Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0390-6078
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
903-7
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12217801-Antigens, CD95,
pubmed-meshheading:12217801-Apoptosis,
pubmed-meshheading:12217801-Calcium-Binding Proteins,
pubmed-meshheading:12217801-Carrier Proteins,
pubmed-meshheading:12217801-Caspase 3,
pubmed-meshheading:12217801-Caspases,
pubmed-meshheading:12217801-DNA,
pubmed-meshheading:12217801-Electrophoretic Mobility Shift Assay,
pubmed-meshheading:12217801-Fusion Proteins, bcr-abl,
pubmed-meshheading:12217801-Humans,
pubmed-meshheading:12217801-Jurkat Cells,
pubmed-meshheading:12217801-K562 Cells,
pubmed-meshheading:12217801-Kv Channel-Interacting Proteins,
pubmed-meshheading:12217801-Leukemia,
pubmed-meshheading:12217801-Protein Binding,
pubmed-meshheading:12217801-Protein-Tyrosine Kinases,
pubmed-meshheading:12217801-Repressor Proteins,
pubmed-meshheading:12217801-Signal Transduction
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pubmed:year |
2002
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pubmed:articleTitle |
Fas signaling and blockade of Bcr-Abl kinase induce apoptotic Hrk protein via DREAM inhibition in human leukemia cells.
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pubmed:affiliation |
Unidad de Genetica Molecular, Hospital Universitario Marques de Valdecilla, Santander, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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