Linked Life Data

1221434

Source:http://linkedlifedata.com/resource/pubmed/id/1221434

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1976-6-2
pubmed:abstractText
The effects of chlorpromazine and fluphenazine on behavior and electroencephalogram (EEG) have been studied in rats in order to find out whether quantitative surface EEG can be reliably used to assess the degree of hypnotic sedative activity of neuroleptic agents. It was found that fluphenazine is about 10 times more potent than chlorpromazine in depressing locomotor activity and variable-interval behavior of rats, while the two drugs were equally potent as regards their synchronizing action on the EEG. This is in accordance with the clinical observation that fluphenazine has less hypnotic side-effects than chlorpromazine and confirms that surface EEG can be a predictive test for hypnotic activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0031-7012
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
520-5
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Relationship between the behavioral and electroencephalographic effects of chlorpromazine and fluphenazine in rats.
pubmed:publicationType
Journal Article