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rdf:type |
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lifeskim:mentions |
umls-concept:C0007137,
umls-concept:C0017262,
umls-concept:C0185117,
umls-concept:C0460004,
umls-concept:C0752095,
umls-concept:C0796358,
umls-concept:C0936012,
umls-concept:C1135935,
umls-concept:C1510941,
umls-concept:C1513387,
umls-concept:C2911684
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pubmed:issue |
9
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|
pubmed:dateCreated |
2002-9-4
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pubmed:abstractText |
A combination of molecular cytogenetic and expression array analysis has been performed on head and neck squamous cell carcinoma (HNSCC) of the oral cavity and supraglottis. These studies were performed to identify consensus regions of chromosomal imbalance and structural rearrangement to determine whether genes located in these genomic regions are subject to alterations in gene expression. Such combinatorial studies may help to identify recurrent patterns of altered gene expression in the context of specific chromosomal changes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1043-3074
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2002 Wiley Periodicals, Inc. Head Neck 24: 874-887, 2002
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pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
874-87
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12211052-Carcinoma, Squamous Cell,
pubmed-meshheading:12211052-Chromosome Aberrations,
pubmed-meshheading:12211052-Chromosome Banding,
pubmed-meshheading:12211052-Cytogenetic Analysis,
pubmed-meshheading:12211052-DNA, Neoplasm,
pubmed-meshheading:12211052-Down-Regulation,
pubmed-meshheading:12211052-Gene Expression Profiling,
pubmed-meshheading:12211052-Head and Neck Neoplasms,
pubmed-meshheading:12211052-Humans,
pubmed-meshheading:12211052-Karyotyping,
pubmed-meshheading:12211052-Nucleic Acid Hybridization,
pubmed-meshheading:12211052-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:12211052-Pilot Projects,
pubmed-meshheading:12211052-RNA, Neoplasm,
pubmed-meshheading:12211052-Tongue Neoplasms,
pubmed-meshheading:12211052-Tumor Cells, Cultured,
pubmed-meshheading:12211052-Up-Regulation
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pubmed:year |
2002
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pubmed:articleTitle |
Molecular cytogenetic analysis of head and neck squamous cell carcinoma: By comparative genomic hybridization, spectral karyotyping, and expression array analysis.
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pubmed:affiliation |
Department of Laboratory Medicine and Pathobiology, The University of Toronto and The University Health Network, Toronto, Ontario, Canada. jeremy.squire@utoronto.ca
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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