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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1976-4-30
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pubmed:abstractText |
Tracheobronchial clearance was measured in nine healthy, nonsmoking adults. Technetium Tc 99m albumin aerosol (mass median diameter, 3 mu; geometric standard deviation, 1.6) was inhaled as a bolus under controlled conditions to achieve reproducible deposition in large airways. Each subject was studied in three seperate three-hour experiments: twice under control conditions and once exposed to 5 ppm sulfur dioxide (pollutant exposure after aerosol inhalation). Lung retention of activity was measured using a gamma camera interfaced to a data storage and retrieval system. The study showed that (1) Both deposition and clearance were highly reproducible in individuals in repeat control studies. (2) Acute exposure to 5 ppm sulfur dioxide had no significant effect (P greater than .05) on mucocillary clearance in resting healthy subjects, except perhaps for a small transient change (P=.05) after one hour. (3) Pulmonary function tests showed a decrease in maximal midexpiratory flow (P less than .01) but no other significant changes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0003-9896
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
521-7
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pubmed:dateRevised |
2009-11-3
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pubmed:meshHeading |
pubmed-meshheading:1217911-Adult,
pubmed-meshheading:1217911-Aerosols,
pubmed-meshheading:1217911-Air,
pubmed-meshheading:1217911-Bronchi,
pubmed-meshheading:1217911-Female,
pubmed-meshheading:1217911-Humans,
pubmed-meshheading:1217911-Male,
pubmed-meshheading:1217911-Radionuclide Imaging,
pubmed-meshheading:1217911-Respiratory Function Tests,
pubmed-meshheading:1217911-Sulfur Dioxide,
pubmed-meshheading:1217911-Technetium,
pubmed-meshheading:1217911-Trachea
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pubmed:year |
1975
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pubmed:articleTitle |
Sulfur dioxide and tracheobronchial clearance in man.
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pubmed:publicationType |
Journal Article
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