Source:http://linkedlifedata.com/resource/pubmed/id/12174909
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2002-8-14
|
| pubmed:abstractText |
Phosphorothioate oligonucleotides ([S]ODNs) contain a modified phosphate backbone. Antisense [S]ODNs targeted to specific oncogenes have been used to varying success in vivo. Carboplatin is a commonly used chemotherapeutic and is associated with chemoresistance in some human tumours. The potential for combined antisense [S]ODNs and carboplatin chemotherapy has only recently been explored in vivo.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0250-7005
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
22
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
2237-45
|
| pubmed:dateRevised |
2003-11-14
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| pubmed:meshHeading |
pubmed-meshheading:12174909-Adenocarcinoma,
pubmed-meshheading:12174909-Animals,
pubmed-meshheading:12174909-Carboplatin,
pubmed-meshheading:12174909-Cell Division,
pubmed-meshheading:12174909-Disease Models, Animal,
pubmed-meshheading:12174909-Genes, myc,
pubmed-meshheading:12174909-Kinetics,
pubmed-meshheading:12174909-Oligodeoxyribonucleotides, Antisense,
pubmed-meshheading:12174909-Rats,
pubmed-meshheading:12174909-Thionucleotides
|
| pubmed:articleTitle |
Enhanced in vivo tumour response from combination of carboplatin and low-dose c-myc antisense oligonucleotides.
|
| pubmed:affiliation |
School of Biomedical Science, Charles Sturt University, Wagga Wagga, NSW, Australia. towalker@csu.edu
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| pubmed:publicationType |
Journal Article
|