Linked Life Data

1217450

Source:http://linkedlifedata.com/resource/pubmed/id/1217450

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1976-4-27
pubmed:abstractText
A new approach to rapid male sterilization was studies by giving a single injection of sclerosing chemical agents (10% silvernitrate, 3.6% Formaldehyde in ehanol, 5% potassium permagnate, 100% ethanol, and 3.6% Formaldehyde) directly into the vas deferens to determine whether blocking the vas has any adverse effects on the testicular function. 2 - Chemical occlusion of vas is quite effective in producing a block in the vas deferens of dogs. 3 - Ethanol injection in the vas deferens caused an atrophy of the testis. Extensive necrossis and exfoliation of the seminiferous elements were conspicuous. These changes increased in severity in 3.6% Formaldehyde in ethanol, 5% potassium permagnate, and 10% silver nitrate solution injected dogs. 4 - Decrease in the testicular contents of RNA, Protein and sialic acid, four weeks after vas occlusion were associated with degenerative changes of the spermatogenic elements. 5 - Testicular cholesterol and total lipids were increased following vas occlusion. 6 - Reduced sialic acid levels in the testis of vas occluded dogs indicates an inhibition of androgen production, which is further reflected in reduced leydig cell function. 7 - The role of vas deferens in determining the fate of a given testis is being discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0587-2421
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
348-53
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
The effects of chemical occlusion of vas deferens on the testicular function of dog: a preliminary study.
pubmed:publicationType
Journal Article