Linked Life Data

12173056

Source:http://linkedlifedata.com/resource/pubmed/id/12173056

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2002-8-12
pubmed:abstractText
Exposure to lowered oxygen pressure at high altitude results in various physiological reactions. The most important response besides hyperventilation is the elevation of the oxygen transport capacity, which simply is achieved by plasma diuresis. Hemoconcentration however not only increases oxygen uptake but also raises blood viscosity, serum osmolality and impairs blood flow. Various observations have suggested that hearing and postural properties deteriorate under these conditions at high altitude. Studies in hypobaric chambers and our own data indicate that the elevated hematocrit levels and hypoxemia may impair the central nervous system functions, resulting in altered speech discrimination, directional hearing, and postural control. However, there is no evidence that cochlear and vestibular sensory cells are affected, whether by acute hypoxia, nor by elevated hematocrit levels up to 58 %. Even an greater increase in serum osmolality or an impaired osmoregulation may not interfere with the outer hair cell function resulting in threshold shift and hearing loss.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0935-8943
pubmed:author
pubmed:issnType
Print
pubmed:volume
81
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
465-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
[Cochlear and vestibular risk at high altitude].
pubmed:affiliation
Klinik und Poliklinik für Hals-, Nasen- und Ohrenkranke, Ludwig-Maximilians-Universität München. klaus.mees@hno.med.uni-muenchen.de
pubmed:publicationType
Journal Article, English Abstract