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pubmed:abstractText |
Barrett's oesophageal epithelium (BE) is clinically important due to the associated inflammatory and malignant complications which are unevenly distributed throughout the BE segment. As the immunoregulatory environment may influence disease manifestations, we analysed the inflammatory and cytokine responses throughout the BE mucosa. We then investigated whether the inflammatory gradient is related to the distribution of metaplastic cell subtypes, epithelial exposure to the components of refluxate, or squamocolumnar cell interactions.
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pubmed:affiliation |
Cancer Cell Unit, Hutchison/MRC Research Centre, Hills Road, Cambridge, and Havering Hospitals NHS Trust, Romford, Essex, UK. rcf@hutchison-mrc.cam.ac.uk
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