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rdf:type |
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lifeskim:mentions |
umls-concept:C0007589,
umls-concept:C0041904,
umls-concept:C0079189,
umls-concept:C0079411,
umls-concept:C0086418,
umls-concept:C0162493,
umls-concept:C0205245,
umls-concept:C0225336,
umls-concept:C0670896,
umls-concept:C1254042,
umls-concept:C1321301,
umls-concept:C1367477,
umls-concept:C1511938
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pubmed:issue |
2
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pubmed:dateCreated |
2002-8-1
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pubmed:abstractText |
Dendritic cells (DCs) can be generated from peripheral blood mononuclear cells (PBMC) after stimulation with exogenous granulocyte-macrophage colony stimulating factor and interleukin (IL)-4. Further, extravasation of monocytes through human endothelial cells can also cause differentiation, maturation, and expression of DC-specific phenotype. However, it is unclear whether human DCs can be generated from monocytes under the influence of xenogeneic endothelial cells in the absence of exogenous cytokines. We therefore analyzed and compared the effect of human and porcine endothelial cells on the differentiation of human monocytes into DC.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD14,
http://linkedlifedata.com/resource/pubmed/chemical/CD40 Ligand,
http://linkedlifedata.com/resource/pubmed/chemical/CD83 antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Drosophila Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DR Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptors
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0041-1337
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
243-52
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12151738-Antigens, CD,
pubmed-meshheading:12151738-Antigens, CD14,
pubmed-meshheading:12151738-CD40 Ligand,
pubmed-meshheading:12151738-Cell Adhesion,
pubmed-meshheading:12151738-Cell Differentiation,
pubmed-meshheading:12151738-Cells, Cultured,
pubmed-meshheading:12151738-Cytokines,
pubmed-meshheading:12151738-Dendritic Cells,
pubmed-meshheading:12151738-Drosophila Proteins,
pubmed-meshheading:12151738-Endothelium, Vascular,
pubmed-meshheading:12151738-HLA-DR Antigens,
pubmed-meshheading:12151738-Humans,
pubmed-meshheading:12151738-Immunoglobulins,
pubmed-meshheading:12151738-Membrane Glycoproteins,
pubmed-meshheading:12151738-Monocytes,
pubmed-meshheading:12151738-Muscle, Smooth, Vascular,
pubmed-meshheading:12151738-Receptors, Cell Surface,
pubmed-meshheading:12151738-Toll-Like Receptors,
pubmed-meshheading:12151738-Up-Regulation
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pubmed:year |
2002
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pubmed:articleTitle |
Differentiation and functional maturation of human CD14(+) adherent peripheral blood monocytes by xenogeneic endothelial cells: up-regulation of costimulation, cytokine generation, and toll-like receptors.
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pubmed:affiliation |
Departments of Surgery, Pathology, and Immunology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. kumart@msnotes.wustl.edu.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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