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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0007104,
umls-concept:C0017262,
umls-concept:C0024554,
umls-concept:C0169665,
umls-concept:C0185117,
umls-concept:C1332737,
umls-concept:C1441616,
umls-concept:C1510438,
umls-concept:C1705523,
umls-concept:C2348519,
umls-concept:C2911684
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|
pubmed:issue |
6
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|
pubmed:dateCreated |
2002-7-18
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|
pubmed:abstractText |
Male breast cancer (MBC) is an uncommon disease, and most of our current knowledge of its biology, natural history and treatment has been extrapolated from data on the disease in women. Information is still needed on the molecular biological properties of male breast tumors and their predictive relevance. Kinase inhibitor proteins (KIPs) p27Kip1 and p21Waf1 negatively regulate cell cycle progression by preventing the passage of cycling cells from G1 to S phase through G1 cyclin-dependent kinase activation. No studies exist on the role of these factors in male breast carcinoma.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jun
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|
pubmed:issn |
0923-7534
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pubmed:author |
pubmed-author:ColleoniMM,
pubmed-author:CuriglianoGG,
pubmed-author:FerrettiGG,
pubmed-author:GennariRR,
pubmed-author:GoldhirschAA,
pubmed-author:MaioranoEE,
pubmed-author:MandalàMM,
pubmed-author:MazzarolGG,
pubmed-author:NolèFF,
pubmed-author:PeruzzottiGG,
pubmed-author:RenneGG,
pubmed-author:RobertsonCC,
pubmed-author:VeronesiPP,
pubmed-author:VialaCC,
pubmed-author:de BrauwPP
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pubmed:issnType |
Print
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pubmed:volume |
13
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
895-902
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12123335-Adult,
pubmed-meshheading:12123335-Aged,
pubmed-meshheading:12123335-Breast Neoplasms,
pubmed-meshheading:12123335-Breast Neoplasms, Male,
pubmed-meshheading:12123335-Cell Cycle Proteins,
pubmed-meshheading:12123335-Cyclin-Dependent Kinase Inhibitor p27,
pubmed-meshheading:12123335-Cyclin-Dependent Kinases,
pubmed-meshheading:12123335-Female,
pubmed-meshheading:12123335-Genetic Markers,
pubmed-meshheading:12123335-Genetic Predisposition to Disease,
pubmed-meshheading:12123335-Humans,
pubmed-meshheading:12123335-Immunohistochemistry,
pubmed-meshheading:12123335-Linear Models,
pubmed-meshheading:12123335-Male,
pubmed-meshheading:12123335-Middle Aged,
pubmed-meshheading:12123335-Oncogene Protein p21(ras),
pubmed-meshheading:12123335-Probability,
pubmed-meshheading:12123335-Prognosis,
pubmed-meshheading:12123335-Retrospective Studies,
pubmed-meshheading:12123335-Sensitivity and Specificity,
pubmed-meshheading:12123335-Sex Factors,
pubmed-meshheading:12123335-Tumor Suppressor Proteins
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pubmed:year |
2002
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|
pubmed:articleTitle |
Recognizing features that are dissimilar in male and female breast cancer: expression of p21Waf1 and p27Kip1 using an immunohistochemical assay.
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|
pubmed:affiliation |
Department of Medicine, European Institute of Oncology, Milan, Italy. giuseppe.curigliano@ieo.it
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pubmed:publicationType |
Journal Article,
Comparative Study
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