Source:http://linkedlifedata.com/resource/pubmed/id/12121395
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2002-7-17
|
| pubmed:abstractText |
The differences between topical corticosteroids are based mainly on their potency, safety and patient acceptability. The aim of this study was to evaluate a mild- to mid-potent topical corticosteroid, desonide 0.05%, on these three parameters in an Australian cohort of patients with facial seborrhoeic or atopic dermatitis. Eighty-one adult patients were randomized to receive desonide 0.05% lotion or its vehicle, applied twice daily for 3 weeks under double-blind conditions. In the active treatment group, 88% of patients had their skin condition cleared or almost cleared and only two patients experienced cutaneous adverse events (rash and pruritus). The acceptability of the lotion was high; 95% of patients stated they would use this topical corticosteroid again. These data support the short-term use of desonide 0.05% lotion as a suitable agent for the short-term treatment of facial dermatitis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0004-8380
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
43
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
186-9
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:12121395-Administration, Topical,
pubmed-meshheading:12121395-Adolescent,
pubmed-meshheading:12121395-Adult,
pubmed-meshheading:12121395-Anti-Inflammatory Agents,
pubmed-meshheading:12121395-Australia,
pubmed-meshheading:12121395-Dermatitis, Atopic,
pubmed-meshheading:12121395-Dermatitis, Seborrheic,
pubmed-meshheading:12121395-Desonide,
pubmed-meshheading:12121395-Dose-Response Relationship, Drug,
pubmed-meshheading:12121395-Double-Blind Method,
pubmed-meshheading:12121395-Drug Administration Schedule,
pubmed-meshheading:12121395-Emulsions,
pubmed-meshheading:12121395-Esthetics,
pubmed-meshheading:12121395-Facial Dermatoses,
pubmed-meshheading:12121395-Female,
pubmed-meshheading:12121395-Follow-Up Studies,
pubmed-meshheading:12121395-Glucocorticoids,
pubmed-meshheading:12121395-Humans,
pubmed-meshheading:12121395-Male,
pubmed-meshheading:12121395-Middle Aged,
pubmed-meshheading:12121395-Probability,
pubmed-meshheading:12121395-Reference Values,
pubmed-meshheading:12121395-Treatment Outcome
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
Efficacy, cutaneous tolerance and cosmetic acceptability of desonide 0.05% lotion (Desowen) versus vehicle in the short-term treatment of facial atopic or seborrhoeic dermatitis.
|
| pubmed:affiliation |
Skin and Cancer Foundation Australia, Darlinghurst, New South Wales, Australia. susisuron@aol.com.au
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|