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pubmed-article:12115316pubmed:abstractTextA high frequency of genetic alterations of the von Hippel-Lindau (VHL) gene and overexpression of the vascular endothelial growth factor (VEGF) gene have been observed independently in human sporadic renal cell carcinoma (RCCs), but to the authors' knowledge the association between the two has not been characterized in primary sporadic RCC. In the current study the authors report the simultaneous comparison of the biallelic inactivation status of the VHL gene and VEGF expression levels in patients with sporadic RCC.lld:pubmed
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pubmed-article:12115316pubmed:copyrightInfoCopyright 2002 American Cancer Society.lld:pubmed
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pubmed-article:12115316pubmed:articleTitleVascular endothelial growth factor overexpression is correlated with von Hippel-Lindau tumor suppressor gene inactivation in patients with sporadic renal cell carcinoma.lld:pubmed
pubmed-article:12115316pubmed:affiliationDepartment of Pathology, Nihon University School of Medicine, Tokyo, Japan.lld:pubmed
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