| pubmed-article:12079347 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12079347 | lifeskim:mentions | umls-concept:C0162807 | lld:lifeskim |
| pubmed-article:12079347 | lifeskim:mentions | umls-concept:C0162327 | lld:lifeskim |
| pubmed-article:12079347 | lifeskim:mentions | umls-concept:C0681842 | lld:lifeskim |
| pubmed-article:12079347 | lifeskim:mentions | umls-concept:C1706765 | lld:lifeskim |
| pubmed-article:12079347 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:12079347 | pubmed:dateCreated | 2002-6-24 | lld:pubmed |
| pubmed-article:12079347 | pubmed:abstractText | Most functional RNA molecules have characteristic secondary structures that are highly conserved in evolution. Here we present a method for computing the consensus structure of a set aligned RNA sequences taking into account both thermodynamic stability and sequence covariation. Comparison with phylogenetic structures of rRNAs shows that a reliability of prediction of more than 80% is achieved for only five related sequences. As an application we show that the Early Noduline mRNA contains significant secondary structure that is supported by sequence covariation. | lld:pubmed |
| pubmed-article:12079347 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12079347 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12079347 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12079347 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:12079347 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12079347 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:12079347 | pubmed:issn | 0022-2836 | lld:pubmed |
| pubmed-article:12079347 | pubmed:author | pubmed-author:HofackerIvo... | lld:pubmed |
| pubmed-article:12079347 | pubmed:author | pubmed-author:FeketeMartinM | lld:pubmed |
| pubmed-article:12079347 | pubmed:author | pubmed-author:StadlerPeter... | lld:pubmed |
| pubmed-article:12079347 | pubmed:copyrightInfo | (c) 2002 Elsevier Science Ltd. | lld:pubmed |
| pubmed-article:12079347 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12079347 | pubmed:day | 21 | lld:pubmed |
| pubmed-article:12079347 | pubmed:volume | 319 | lld:pubmed |
| pubmed-article:12079347 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12079347 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12079347 | pubmed:pagination | 1059-66 | lld:pubmed |
| pubmed-article:12079347 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:12079347 | pubmed:meshHeading | pubmed-meshheading:12079347... | lld:pubmed |
| pubmed-article:12079347 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12079347 | pubmed:articleTitle | Secondary structure prediction for aligned RNA sequences. | lld:pubmed |
| pubmed-article:12079347 | pubmed:affiliation | Institut für Theoretische Chemie, Universität Wien, Währingerstrasse 17, Austria. | lld:pubmed |
| pubmed-article:12079347 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12079347 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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