Source:http://linkedlifedata.com/resource/pubmed/id/12069629
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2002-6-18
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pubmed:abstractText |
Brownian and molecular dynamics simulations of a lipid bilayer are described, and the calculated frequency-dependent (13)C NMR T(1) relaxation times are compared with experiment. A consistent model emerges. Through fast internal motions, individual lipids average themselves into relatively cylindrical shapes on the 100 ps time scale and "wobble" in a cone-like potential on the nanosecond time scale. These motions take place in a highly fluid environment, much like a liquid alkane. Lateral diffusion of the lipids is on a significantly longer time scale because of restrictions at the bilayer/water interface, not because the interior of the bilayer is highly viscous.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0001-4842
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
438-46
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading | |
pubmed:year |
2002
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pubmed:articleTitle |
Lipid bilayers, NMR relaxation, and computer simulations.
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pubmed:affiliation |
Laboratory of Biophysics, Center for Biologics Evaluation and Research, FDA, 1401 Rockville Pike, Rockville, Maryland 20852-1448, USA.
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pubmed:publicationType |
Journal Article,
Review
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