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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2002-6-12
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pubmed:abstractText |
Hypoxia-inducible factor (HIF)-1alpha is a transcription factor that supports the adaptation of human cancer cells to hypoxia and is involved in various pathways supporting tumor growth and progression. The aim of this study was to determine the prognostic influence of HIF-1alpha expression in patients with advanced-stage breast cancer, evident by positive lymph nodes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:Austrian Breast and Colorectal Cancer Study Group,
pubmed-author:BirnerPeterP,
pubmed-author:GnantMichaelM,
pubmed-author:HausmaningerHubertH,
pubmed-author:JakeszRaimundR,
pubmed-author:KubistaErnstE,
pubmed-author:KwasnyWernerW,
pubmed-author:OberhuberGeorgG,
pubmed-author:SamoniggHellmutH,
pubmed-author:SchindlMonikaM,
pubmed-author:SchoppmannSebastian FSF
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1831-7
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12060624-Breast Neoplasms,
pubmed-meshheading:12060624-Disease-Free Survival,
pubmed-meshheading:12060624-Female,
pubmed-meshheading:12060624-Humans,
pubmed-meshheading:12060624-Hypoxia-Inducible Factor 1, alpha Subunit,
pubmed-meshheading:12060624-Immunoenzyme Techniques,
pubmed-meshheading:12060624-Lymph Nodes,
pubmed-meshheading:12060624-Lymphatic Metastasis,
pubmed-meshheading:12060624-Microscopy, Confocal,
pubmed-meshheading:12060624-Middle Aged,
pubmed-meshheading:12060624-Neoplasm Invasiveness,
pubmed-meshheading:12060624-Prognosis,
pubmed-meshheading:12060624-Prospective Studies,
pubmed-meshheading:12060624-Receptor, erbB-2,
pubmed-meshheading:12060624-Receptors, Estrogen,
pubmed-meshheading:12060624-Survival Rate,
pubmed-meshheading:12060624-Transcription Factors,
pubmed-meshheading:12060624-Tumor Suppressor Protein p53
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pubmed:year |
2002
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pubmed:articleTitle |
Overexpression of hypoxia-inducible factor 1alpha is associated with an unfavorable prognosis in lymph node-positive breast cancer.
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pubmed:affiliation |
Institute of Clinical Pathology, Department of Surgery, University of Vienna Medical School, Währinger Gürtel 18-20, A-1090 Vienna, Austria.
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pubmed:publicationType |
Journal Article,
Comparative Study
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