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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2002-6-12
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pubmed:abstractText |
Patients with high-grade transitional-cell carcinoma (TCC) of the bladder frequently experience recurrence and progress and have a low response rate to chemotherapy in metastatic TCC. In this study, we evaluated the feasibility and long-term efficacy of suicide-gene therapy using adenovirus (Ad)-mediated herpes simplex virus thymidine kinase gene (HSV-TK) and prodrug ganciclovir (GCV) as a potential therapeutic approach in murine-orthotopic models of TCC.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0919-8172
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
261-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12060439-Adenoviridae,
pubmed-meshheading:12060439-Animals,
pubmed-meshheading:12060439-Antiviral Agents,
pubmed-meshheading:12060439-Carcinoma, Transitional Cell,
pubmed-meshheading:12060439-Disease Models, Animal,
pubmed-meshheading:12060439-Female,
pubmed-meshheading:12060439-Ganciclovir,
pubmed-meshheading:12060439-Gene Therapy,
pubmed-meshheading:12060439-Mice,
pubmed-meshheading:12060439-Mice, Inbred C3H,
pubmed-meshheading:12060439-Simplexvirus,
pubmed-meshheading:12060439-Thymidine Kinase,
pubmed-meshheading:12060439-Urinary Bladder Neoplasms
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pubmed:year |
2002
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pubmed:articleTitle |
Adenovirus-mediated suicide-gene therapy in an orthotopic murine bladder tumor model.
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pubmed:affiliation |
Department of Urology, Korea University College of Medicine, Seoul, Korea. jcheon@ns.kumc.or.kr
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pubmed:publicationType |
Journal Article
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