Linked Life Data

12055832

Source:http://linkedlifedata.com/resource/pubmed/id/12055832

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2002-6-11
pubmed:abstractText
Leishmania species of the subgenus Viannia account for 88% of all cases of leishmaniasis recorded in Colombia. Correct diagnosis is essential as infection with members of this subgenus can produce disfiguring destruction of the mucosa. Several methods are available to diagnose leishmaniasis in clinical samples. More recently, the polymerase chain reaction (PCR) has been used, with varying sensitivities and specificities depending on the primers used. In this paper we report on the sensitivity and specificity of PCR primers B1/B2 used on clinical samples and compare their use to the conventional parasitological methods. PCR alone is more sensitive than any single conventional method used, but a combination of conventional methods produced comparable sensitivity. PCR is well suited for use in selected cases and as a test for mucosal leishmaniasis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0035-9203
pubmed:author
pubmed:issnType
Print
pubmed:volume
96 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S165-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Validation of the polymerase chain reaction for the diagnosis of human cutaneous leishmaniasis in north-west Colombia.
pubmed:affiliation
Instituto Colombiano de Medicina Tropical Antonio Roldan Betancur, Medellin, Colombia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Validation Studies