Source:http://linkedlifedata.com/resource/pubmed/id/12039409
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2002-5-31
|
| pubmed:abstractText |
Interleukin-10 (IL-10) secretion affects the inducibility of experimental autoimmune encephalomyelitis and the outcome of multiple sclerosis (MS). Here, we report that a G to A polymorphism in the IL-10 promoter at position -2849 is significantly associated with low IL-10 production. The frequency of this polymorphism is lower among patients with primary progressive compared with patients with relapse-onset MS and control persons.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0198-8859
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
63
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
281-5
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:12039409-Adult,
pubmed-meshheading:12039409-Disease Susceptibility,
pubmed-meshheading:12039409-Female,
pubmed-meshheading:12039409-HLA-DR2 Antigen,
pubmed-meshheading:12039409-Humans,
pubmed-meshheading:12039409-Interleukin-10,
pubmed-meshheading:12039409-Male,
pubmed-meshheading:12039409-Middle Aged,
pubmed-meshheading:12039409-Multiple Sclerosis, Chronic Progressive,
pubmed-meshheading:12039409-Multiple Sclerosis, Relapsing-Remitting,
pubmed-meshheading:12039409-Polymorphism, Genetic
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
Frequency of functional interleukin-10 promoter polymorphism is different between relapse-onset and primary progressive multiple sclerosis.
|
| pubmed:affiliation |
Department of Clinical Epidemiology, University of Glasgow, Scotland, United Kingdom.
|
| pubmed:publicationType |
Journal Article
|