Linked Life Data

1202076

Source:http://linkedlifedata.com/resource/pubmed/id/1202076

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1976-3-1
pubmed:abstractText
A description is given of a gas chromatographic method for the determination of hydralazine in plasma. On treatment with nitrous acid, hydralazine is converted into tetrazolo[1,5-a]phthalazine, a stable compound that can be extracted from biological material with organic solvent and determined quantitiatively by gas-liquid chromatography. The 4-methyl analogue of hydralazine serves as internal standard for derivatization, extraction and gas chromatography. The sensitivity (10 ng per ml of plasma) is sufficient to monitor plasma levels in man after administration of single oral doses of 50 mg of Apresoline¿. The known metabolites do not interfere.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0021-9673
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
87-92
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
The determination of hydralazine in plasma by gas-liquid chromatography.
pubmed:publicationType
Journal Article