12014850

Source:http://linkedlifedata.com/resource/pubmed/id/12014850

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0012634, umls-concept:C0043119, umls-concept:C0086418, umls-concept:C0231341, umls-concept:C1704259, umls-concept:C1705987
pubmed:issue	1-2
pubmed:dateCreated	2002-5-16
pubmed:abstractText	Werner syndrome is the hallmark premature aging disease, where the patients appear much older than their chronological age. The Werner protein, defective in this disorder, is a DNA helicase and an exonuclease, and it participates in pathways of DNA repair, recombination, transcription and replication. The function and role of this protein is discussed in the light of how it functions in the aging process.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/100930043
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:issn	1389-5729
pubmed:author	pubmed-author:BohrVilhelm AVA, pubmed-author:BroshRobert MRMJr, pubmed-author:KarmakarParimalP, pubmed-author:OpreskoPatriciaP, pubmed-author:von KobbeCayetanoC
pubmed:issnType	Print
pubmed:volume	3
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	89-94
pubmed:dateRevised	2004-11-17
pubmed:meshHeading	pubmed-meshheading:12014850-Aging, pubmed-meshheading:12014850-Humans, pubmed-meshheading:12014850-Protein Binding, pubmed-meshheading:12014850-Werner Syndrome
pubmed:year	2002
pubmed:articleTitle	Pathways defective in the human premature aging disease Werner syndrome.
pubmed:affiliation	Laboratory of Molecular Gerontology, National Institute on Aging, NIH, Baltimore, MD 21224, USA. vbohr@nih.gov
pubmed:publicationType	Journal Article